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Structured Review

Simcyp pediatric platform version 14
Pediatric Platform Version 14, supplied by Simcyp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pediatric+platform+version+14/simulator+version+15/pmc05321811-70-12-11
Average 90 stars, based on 1 article reviews
pediatric platform version 14 - by Bioz Stars, 2026-10
90/100 stars

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Related Articles

Protein Concentration:

Article Title: Characterization of Contributing Factors to Variability in Morphine Clearance Through PBPK Modeling Implemented With OCT1 Transporter
Article Snippet: .. The PK simulations of morphine in children were conducted using the Simcyp Pediatric platform version 14 that takes age‐dependent anatomic and physiological changes into account (i.e., age‐dependent organ size, cardiac output, microsomal protein concentration per organ, plasma protein concentration, hematocrit level, UGT2B7 protein expression level, and glomerular filtration rate)., The Simcyp Pediatric simulator generates age‐dependent anatomic and physiological parameters as system parameters for virtual pediatric subjects based on the equation describing the relationship between subject's age and each parameter reported by Johnson et al ., except the age‐dependent OCT1 protein expression. ..

Clinical Proteomics:

Article Title: Characterization of Contributing Factors to Variability in Morphine Clearance Through PBPK Modeling Implemented With OCT1 Transporter
Article Snippet: .. The PK simulations of morphine in children were conducted using the Simcyp Pediatric platform version 14 that takes age‐dependent anatomic and physiological changes into account (i.e., age‐dependent organ size, cardiac output, microsomal protein concentration per organ, plasma protein concentration, hematocrit level, UGT2B7 protein expression level, and glomerular filtration rate)., The Simcyp Pediatric simulator generates age‐dependent anatomic and physiological parameters as system parameters for virtual pediatric subjects based on the equation describing the relationship between subject's age and each parameter reported by Johnson et al ., except the age‐dependent OCT1 protein expression. ..

Expressing:

Article Title: Characterization of Contributing Factors to Variability in Morphine Clearance Through PBPK Modeling Implemented With OCT1 Transporter
Article Snippet: .. The PK simulations of morphine in children were conducted using the Simcyp Pediatric platform version 14 that takes age‐dependent anatomic and physiological changes into account (i.e., age‐dependent organ size, cardiac output, microsomal protein concentration per organ, plasma protein concentration, hematocrit level, UGT2B7 protein expression level, and glomerular filtration rate)., The Simcyp Pediatric simulator generates age‐dependent anatomic and physiological parameters as system parameters for virtual pediatric subjects based on the equation describing the relationship between subject's age and each parameter reported by Johnson et al ., except the age‐dependent OCT1 protein expression. ..

Filtration:

Article Title: Characterization of Contributing Factors to Variability in Morphine Clearance Through PBPK Modeling Implemented With OCT1 Transporter
Article Snippet: .. The PK simulations of morphine in children were conducted using the Simcyp Pediatric platform version 14 that takes age‐dependent anatomic and physiological changes into account (i.e., age‐dependent organ size, cardiac output, microsomal protein concentration per organ, plasma protein concentration, hematocrit level, UGT2B7 protein expression level, and glomerular filtration rate)., The Simcyp Pediatric simulator generates age‐dependent anatomic and physiological parameters as system parameters for virtual pediatric subjects based on the equation describing the relationship between subject's age and each parameter reported by Johnson et al ., except the age‐dependent OCT1 protein expression. ..



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90
Simcyp pediatric platform version 14
Pediatric Platform Version 14, supplied by Simcyp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pediatric+platform+version+14/simulator+version+15/pmc05321811-70-12-11
Average 90 stars, based on 1 article reviews
pediatric platform version 14 - by Bioz Stars, 2026-10
90/100 stars
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